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Study identifier: NCT05190991 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Safety and Efficacy of RPH-104 Used to Prevent Recurrent Fever Attacks in Adult Patients With Colchicine Resistant or Colchicine Intolerant Familial Mediterranean Fever

Condition: Familial Mediterranean Fever · FMF  ·  Sponsor: R-Pharm International, LLC

PhasePhase 2
Planned participants60
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

The purpose of this study is to assess safety and efficacy of the long-term treatment with RPH-104 at doses of 80 or 160 mg once every 2 weeks (q2w) in patients with familial Mediterranean fever (FMF) with colchicine resistance or intolerance (i.e. colchicine resistant, crFMF), who completed the core study, during which they received at least one dose of RPH-104 (i.e. study patient population).

This description comes directly from the study's public registry record.

Talk to the study team

Yulia Karpova  ·  +7 495 956 79 37  ·  jn.karpova@inbox.ru

Marina Beloukhova  ·  +7 495 956 79 37  ·  beloukhova@partners.rpharm.ru

Always discuss trial participation with your own doctor first.

Locations (8)

Center of Medical Genetics and Primary Health Care LLCYerevan, ArmeniaRecruiting
FSBEI HE First Moscow State Medical University named after I.M. SechenovMoscow, RussiaRecruiting
Moscow Multidisciplinary Scientific and Clinical Center named after S.P. BotkinMoscow, RussiaRecruiting
Medical Technologies Ltd.Saint Petersburg, RussiaRecruiting
Terafarm, LlcStavropol, RussiaRecruiting
Hacettepe University Faculty of MedicineAnkara, Turkey (Türkiye)Recruiting
Istanbul University Istanbul Faculty of MedicineIstanbul, Turkey (Türkiye)Recruiting
Istanbul University Cerrahpasa Faculty of MedicineIstanbul, Turkey (Türkiye)Recruiting

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Source record: clinicaltrials.gov/study/NCT05190991