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Study identifier: NCT05189821 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

RFA Treatment for Papillary Thyroid Microcarcinoma

Condition: Papillary Thyroid Microcarcinoma  ·  Sponsor: Columbia University

PhaseN/A
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Thyroid surgery has always been the mainstay of treatment for thyroid cancer. Thyroid surgery carries a low risk of complications that include recurrent or superior laryngeal nerve injury leading to voice changes, hypoparathyroidism, hypothyroidism with need for thyroid hormone supplementation, and unsightly scarring. Although many patients with thyroid cancer find these risks acceptable, these risks are sometimes less acceptable to patients with benign disease. In an era when the medical field is treating thyroid diseases less aggressively, there is a pressing need to identify approaches to treat indolent malignant disease less invasively. The purpose of this observational study is to evaluate the efficacy and safety of Radiofrequency Ablation (RFA) for treatment of Papillary Thyroid Microcarcinoma (PTMC) in patients that have already agreed to RFA procedure based on treating physician recommendation. This is a data collection study in which we ask participants to give us access to information generated before and after RFA treatment of their condition. The RFA procedure uses image guidance to place an electrode through the skin into the target tumor. In RFA, high-frequency electrical currents are passed through an electrode, creating a small region of heat to treat the lesion.

This description comes directly from the study's public registry record.

Talk to the study team

Jennifer H Kuo, MD MS  ·  212-305-6969  ·  jhk2029@cumc.columbia.edu

Vilma Rosario  ·  vr2222@cumc.columbia.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Columbia UniversityNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05189821