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Study identifier: NCT05189262 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Cardiopulmonary Bypass Induced Red Blood Cell Lysis

Condition: Cardiopulmonary Bypass · Cardiac Surgery · Kidney Injury, Acute  ·  Sponsor: University of Maryland, Baltimore

PhaseN/A
Planned participants150
Who can joinAll sexes, 18 Years to 88 Years
Healthy volunteersNo

About this study

Studying the dynamics of red blood cell lysis, pfH, protective proteins and organ injury, limits will be set for safe levels of pfH following the use of CPB. These results will be compared to existing laboratory-based methods for determining red blood cell damage to predict CPB assist device safety. Further, results from the studies described in this proposal will help develop therapeutic strategies to benefit patients by early detection of pfH and clearance protein levels that occur during CPB.

This description comes directly from the study's public registry record.

Talk to the study team

Paul W Buehler, PhD  ·  14107065171  ·  pbuehler@som.umaryland.edu

Tobi Rowden, RN  ·  4107064061  ·  trowden@som.umaryland.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Center for Blood Oxygen Transport and HemostasisBaltimore, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05189262