Condition: Positron-Emission Tomography · Sponsor: First Affiliated Hospital of Fujian Medical University
Primary aldosteronism is the most common cause of secondary hypertension. The two main types of primary aldosteronism are aldosteronoma(30%) and adrenal hyperplasia(60%). The gold standard that determines the diagnosis and treatment strategy of primary aldosteronism is adrenal vein sampling(AVS), but the success rate is only about 80%. Using CXCR4 as a probe for 68Ga-Pentixafor PET/CT imaging can guide the classification diagnosis and treatment strategy of primary aldosteronism, which is a favorable supplement to AVS. Superselective adrenal artery embolization(SAAE) and laparoscopy are the main operation treatments for primary aldosteronism. SAAE is an invasive interventional operation. It is a novel way to evaluate the changes in the structure and function of adrenal tissue pre-postoperative SAAE by using the changes in 68Ga-Pentixafor PET/CT imaging.
This description comes directly from the study's public registry record.
Weibing Miao, MD · 86-0591-87981618 · miaoweibing@126.com
Jinxiu Lin, MD · 86-13799777113 · linjinxiu@aliyun.com
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| Department of Nuclear Medicine, First Affiliated Hospital of Fujian Medical University | Fuzhou, Fujian, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05188872