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Study identifier: NCT05188118 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Rapid Sequencing of Approved Therapies in Patients with Metastatic or Unresectable Clear Cell Renal Cell Carcinoma

Condition: Renal Cell Carcinoma  ·  Sponsor: Icahn School of Medicine at Mount Sinai

PhaseEARLY_Phase 1
Planned participants20
Who can joinAll sexes, 18 Years to 99 Years
Healthy volunteersNo

About this study

This is a pilot, single-center, single-arm study where 20 patients with metastatic or unresectable clear cell renal cell carcinoma will receive same sequential treatment strategy (Cabozantinib for 12 weeks, then proceed with Ipilimumab plus Nivolumab immunotherapy x4 over 12 weeks, then subsequent therapies depending on treatment response for another 12 weeks \[Nivolumab for CR/PR/SD, Cabozantinib or Lenvatinib/Everolimus for PROG\]).

This description comes directly from the study's public registry record.

Talk to the study team

Che-Kai Tsao, MD  ·  212-824-8782  ·  che-kai.tsao@mssm.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Icahn School of Medicine at Mount SinaiNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05188118