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Study identifier: NCT05183035 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

Condition: Acute Myeloid Leukemia  ·  Sponsor: PedAL BCU, LLC

PhasePhase 3
Planned participants130
Who can joinAll sexes, 29 Days to 21 Years
Healthy volunteersNo

About this study

A study to evaluate if the randomized addition of venetoclax to a chemotherapy backbone (fludarabine/cytarabine/gemtuzumab ozogamicin \[GO\]) improves survival of children/adolescents/young adults with acute myeloid leukemia (AML) in 1st relapse who are unable to receive additional anthracyclines, or in 2nd relapse.

This description comes directly from the study's public registry record.

Talk to the study team

Gwen Nichols, MD  ·  914-821-8217  ·  gwen.nichols@lls.org

Michel Zwaan  ·  +31 88 972 5206  ·  c.m.zwaan@prinsesmaximacentrum.nl

Always discuss trial participation with your own doctor first.

Locations (90)

Phoenix Children's HospitalPhoenix, Arizona, United StatesRecruiting
Arkansas Children's HospitalLittle Rock, Arkansas, United StatesRecruiting
MemorialCare Miller Children's and Women's Hospital Long BeachLong Beach, California, United StatesRecruiting
Children's Hospital of Orange County Main Campus - OrangeOrange, California, United StatesRecruiting
Benioff Children's Hospital - Mission BaySan Francisco, California, United StatesRecruiting
Children's Hospital ColoradoAurora, Colorado, United StatesRecruiting
Yale UniversityNew Haven, Connecticut, United StatesRecruiting
Nemours Alfred I. Dupont Hospital for ChildrenWilmington, Delaware, United StatesRecruiting
Children's National - Main HospitalWashington D.C., District of Columbia, United StatesRecruiting
Golisano Children's Hospital of Southwest FloridaFort Myers, Florida, United StatesRecruiting
University of Florida Health Shands Children's HospitalGainesville, Florida, United StatesRecruiting
Nemours Children's Specialty Care JacksonvilleJacksonville, Florida, United StatesRecruiting

+ 78 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05183035