Condition: Hodgkin Lymphoma · Non Hodgkin Lymphoma · Sponsor: Angiocrine Bioscience
High-dose chemotherapy followed by blood stem cell transplantation is administered to lymphoma patients with an intention to cure. However, high-dose chemotherapy simultaneously causes damage to healthy tissues that frequently result in severe complications that lead to hospitalization and can be life threatening. These severe complications involve the blood, immune, gastro-intestinal systems, and other vital organs. The purpose of this study is to determine if experimental therapy AB-205 (study drug) can prevent or reduce the occurrence and duration of the severe chemotherapy related complications when compared to placebo in patients with lymphoma undergoing treatment with high-dose chemotherapy and blood stem cell transplantation. All patients, whether treated with AB-205 or placebo, will receive standard preventive and supportive care therapies.
This description comes directly from the study's public registry record.
Contact details are listed per location below or on the registry record.
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| Banner MD Anderson Cancer Center | Gilbert, Arizona, United States | — |
| City of Hope Comprehensive Cancer Center | Duarte, California, United States | — |
| University of California, Los Angeles | Los Angeles, California, United States | — |
| UC Davis Comprehensive Cancer Center | Sacramento, California, United States | — |
| UC San Diego Moores Cancer Center | San Diego, California, United States | — |
| Sarah Cannon Research Institute, Colorado | Denver, Colorado, United States | — |
| Medstar Georgetown University Hospital | Washington D.C., District of Columbia, United States | — |
| University of Miami - Sylvester Comprehensive Cancer Center | Miami, Florida, United States | — |
| University of South Florida (USF) - H. Lee Moffitt Cancer Center and Research Institute | Tampa, Florida, United States | — |
| Emory University - Winship Cancer Institute | Atlanta, Georgia, United States | — |
| University of Illinois Cancer Center | Chicago, Illinois, United States | — |
| Indiana University Simon Comprehensive Cancer Center | Indianapolis, Indiana, United States | — |
+ 16 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT05181540