Condition: Chronic Wounds · Biofilm Infection · Trans-epidermal Water Loss (TEWL) · Sponsor: University of Pittsburgh
This work is based on DFU patients, seeks to conduct a fully powered clinical study testing i) If DFU with a history of biofilm infection closes with deficient barrier function. ii) whether such functionally deficient wound closure, manifested as high TEWL, is associated with greater wound recurrence. The primary parent study will also address molecular mechanisms implicated in biofilm-induced loss of skin epithelial barrier integrity in DFU patients.
This description comes directly from the study's public registry record.
Piya Das Ghatak, PhD, MS · 4126240422 · piya.dasghatak@pitt.edu
Shomita S Steiner, PhD, MS · 463•236•8770 · SSTEINER@pitt.edu
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| University of Arizona | Tucson, Arizona, United States | Recruiting |
| UPMC Wound Healing Services at UPMC Passavant | Cranberry Township, Pennsylvania, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05172089