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Study identifier: NCT05167994 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Preoperative IMRT With Anlotinib and Penpulimab for Localized Sarcoma (SPARE-01)

Condition: Sarcoma,Soft Tissue · Extremity · Trunk  ·  Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences

PhasePhase 2
Planned participants30
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

To investigate the safety and efficacy of preoperative IMRT and concurrent Anlotinib Hydrochloride for primary truncal or extremity soft tissue sarcoma; To investigate the Quality of life and extremity function post-combination treatment; To study the mechanism of radio-sensitizing effects of Anlotinib Hydrochloride and Penpulimab for primary truncal or extremity soft tissue sarcoma; To assess the relationship between the MRI imaging, pathological findings and local control.

This description comes directly from the study's public registry record.

Talk to the study team

Ning-Ning Lu  ·  +868611804268  ·  Ning-Ning.Lu@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Radiotherapy Department of Cancer Hospital, Chinese Academy of Medical SciencesBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05167994