Condition: Diabetes Mellitus, Type 2 · PreDiabetes · Insulin Resistance · Sponsor: Stanford University
This 12-week controlled diet and weight intervention study seeks to define the molecular pathways that link excess body weight to the development of insulin resistance (IR). Blood, adipose and stool are sampled at three timepoints; baseline, peak weight (4 weeks) and post weight loss to monitor changes in cellular processes. Additionally, direct insulin sensitivity testing, and radiological measurement of visceral fat and intrahepatic fat content is measured at three timepoints to correlate clinical indices with cellular changes.
This description comes directly from the study's public registry record.
Ekrem M Ayhan, BS · 908-619-5381 · ayhane@stanford.edu
Dalia Perelman, MS, RD · daliap@stanford.edu
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| Stanford University | Stanford, California, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05165706