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Study identifier: NCT05157126 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Gentamicin Open Tibia Study

Condition: Fracture Open Tibia  ·  Sponsor: University of California, San Francisco

PhasePhase 4
Planned participants890
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Local application of antibiotics directly to the traumatic wound is a promising treatment for the prevention of infection after open tibia fractures, which are a significant source of disease burden globally, particularly in low-income countries. This study aims to measure the effect of locally applied gentamicin on risk of infection for open tibial fractures in Tanzania. If proven effective, local gentamicin would be a highly cost-effective strategy to reduce complications and disability from open tibial fractures that could impact care in both high- and low-income countries.

This description comes directly from the study's public registry record.

Talk to the study team

David W Shearer, MD, MPH  ·  628-206-8812  ·  david.shearer@ucsf.edu

Tigist Belaye, MPA  ·  628-206-8812  ·  tigist.belaye@ucsf.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Muhimbili Orthopaedic InstituteDar es Salaam, TanzaniaRecruiting

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Source record: clinicaltrials.gov/study/NCT05157126