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Study identifier: NCT05154799 Synced from ClinicalTrials.gov · July 29, 2026
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Developmental Coordination Disorder

Condition: Motor Skills Disorders · Neurodevelopmental Disorders  ·  Sponsor: Hospices Civils de Lyon

PhaseNA
Planned participants280
Who can joinAll sexes, 9 Years to 40 Years
Healthy volunteersYes

About this study

Developmental Coordination Disorder (DCD) corresponds to a clumsiness, a slowness and an inaccuracy of motor performance. This neurodevelopmental disorder affects 6% of school-aged children, and disturbs daily life activities and academic performances. The etiology of DCD is still unknown. An understanding of this disorder is necessary to improve interventions and therefore quality of life of these people. A deficit of the so-called internal models is the most commonly described hypothesis of DCD. Indeed, children with DCD exhibit difficulties in predictive control. Internal models, useful for motor control, are closely related to the sensory system, as they are elaborated on and constantly fed by sensory feedback. Deficits in sensory performance are described in DCD, mostly in the visual system, which could in turn partly explain poor motor performance. However, visuo-perceptual deficits cannot explain the entire motor difficulties because some activities in daily life, as buttoning a shirt, are often performed without visual control. Although the integrity of proprioceptive and tactile systems is necessary for the building of internal models, and therefore for a stable motor control, these sensory systems have been very little investigated in DCD. Moreover, using a tool is often disturbed in children with DCD. In neurotypical subjects, tool use induces a plasticity of body representation, as reflected by modifications of movement kinematics after tool use. Proprioceptive …

This description comes directly from the study's public registry record.

Talk to the study team

Alessandro FARNE, Dr  ·  4 72 91 34 17  ·  alessandro.farne@inserm.fr

Marion NAFFRECHOUX, PhD Student  ·  6 38 64 54 60  ·  marion.naffrechoux@inserm.fr

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Locations (1)

Equipe IMPACT du CRNL INSERM U1028, CNRS UMR 5292Bron, Auvergne-Rhône-Alpes, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT05154799