Condition: Obstructive Sleep Apnea Syndrome · Sponsor: CHU de Reims
The obstructive sleep apnea syndrome (OSAS) involves recurrent sleep-related upper airways (UA) collapse. UA mechanical properties and neural control are altered, imposing a mechanical load on inspiration. UA collapse does not occur during wakefulness, hence arousal-dependent compensation. Experimental inspiratory loading in normal subjects elicits respiratory-related cortical activity during wakefulness. The objective of this study is to test whether awake OSAS patients would exhibit a similar cortical activity. Whether or not such cortical compensatory mechanisms have cognitive consequences would be also analyze.
This description comes directly from the study's public registry record.
Claire Launois · 3 26 78 83 70 · claunois@chu-reims.fr
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| Chu Reims | Reims, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05147649