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Study identifier: NCT05145816 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Phase 1/2a Study of Belantamab Mafodotin in Relapsed or Refractory AL Amyloidosis

Condition: AL Amyloidosis · Amyloidosis  ·  Sponsor: University of Texas Southwestern Medical Center

PhasePhase 1/Phase 2
Planned participants37
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this study is to test the safety of drug, Belantamab Mafodotin, and see what effects (good and bad) it has on people who take it and have amyloidosis, and to determine the most effective dose of the drug. The study will have 2 phases (parts). The first phase of the study will test different doses of Belantamab Mafodotin. The second phase will test Belantamab Mafodotin at the dose level found to be safe and effective in phase 1

This description comes directly from the study's public registry record.

Talk to the study team

Donglan Xia  ·  214-648-7097  ·  Donglan.Xia@UTSouthwestern.edu

Always discuss trial participation with your own doctor first.

Locations (3)

Vanderbilt Ingram Cancer CenterNashville, Tennessee, United StatesNot Yet Recruiting
UT Southwestern Medical CenterDallas, Texas, United StatesRecruiting
Huntsman Cancer Institute, University of UtahSalt Lake City, Utah, United StatesNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT05145816