Condition: Epiretinal Membrane · Sponsor: Jaeb Center for Health Research
Vitrectomy to remove an epiretinal membrane (ERM) is one of the most common procedures performed by retinal surgeons. Patients who present with significant macular changes on optical coherence tomography (OCT) but relatively good vision are often advised to defer surgery until vision declines to 20/40 or worse. However, it is unknown if delaying surgery, which allows the foveal architecture to remain compromised and potentially to deteriorate, results in worse visual acuity outcomes than if surgery is performed earlier. In addition, there is a need to better understand predictors of outcomes when surgery is performed and predictors of progression when surgery is deferred. Finally, one of the most common presenting symptoms from an ERM is distortion or metamorphopsia. There are several objective measures of metamorphopsia but none have ever been employed to evaluate ERMs in a randomized clinical trial (RCT) and their usefulness is unknown. The purposes of this study are to better understand the optimal timing of surgery to produce the best visual result, to better understand predictors of outcomes in those who undergo surgery and predictors of progression in those whose are observed, and to better characterize and evaluate the usefulness of metamorphopsia and reading speed measures.
This description comes directly from the study's public registry record.
Contact details are listed per location below or on the registry record.
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| Mayo Clinic Arizona | Scottsdale, Arizona, United States | Recruiting |
| Kent W. Small, MD, AMC | Glendale, California, United States | Recruiting |
| Salehi Retina Institute Inc. | Huntington Beach, California, United States | Recruiting |
| Loma Linda University | Loma Linda, California, United States | Recruiting |
| Retina Vitreous Associates, Northern California Retina Vitreous Assoc Medical Group, Inc. | Mountain View, California, United States | Recruiting |
| East Bay Retina Consultants, Inc. | Oakland, California, United States | Recruiting |
| Regents of the University of California, Davis, DBA University of California, Davis | Sacramento, California, United States | Recruiting |
| Macula Retina Vitreous Institute | Torrance, California, United States | Recruiting |
| Florida Retina Institute, James A. Staman, MD, PA- Jacksonville | Jacksonville, Florida, United States | Recruiting |
| Sarasota Retina Institute | Sarasota, Florida, United States | Recruiting |
| SEASHORE RETINA LLC DBA Retina Specialists of Tampa | Wesley Chapel, Florida, United States | Recruiting |
| Southeast Retina Center, P.C. | Augusta, Georgia, United States | Recruiting |
+ 36 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT05145491