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Study identifier: NCT05145400 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Isa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma

Condition: Multiple Myeloma · Cancer  ·  Sponsor: UNC Lineberger Comprehensive Cancer Center

PhasePhase 2
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This research study is investigating the safety and effectiveness of using combination of isatuximab, lenalidomide and dexamethasone for the treatment of newly diagnosed multiple myeloma (MM). The study team will use lower doses than is currently standard for these drugs. Lower doses will be used to avoid or possibly reduce any unwanted side effects commonly associated with these drugs. Using lower doses of the combination isatuximab, lenalidomide and dexamethasone, has not been approved by the Food and Drug Administration (FDA) for the treatment of newly diagnosed MM.

This description comes directly from the study's public registry record.

Talk to the study team

Shamina Williams  ·  919-966-4432  ·  Shamina_Williams@med.unc.edu

Lori Stravers  ·  919-966-4432  ·  Lori_Stravers@med.unc.edu

Always discuss trial participation with your own doctor first.

Locations (5)

University of North Carolina at Chapel Hill, Lineberger Comprehensive Cancer CenterChapel Hill, North Carolina, United StatesRecruiting
Levine Cancer InstituteCharlotte, North Carolina, United StatesRecruiting
Duke Comprehensive Cancer CenterDurham, North Carolina, United StatesRecruiting
Novant Health New Hanover Regional Medical CenterWilmington, North Carolina, United StatesRecruiting
The Ohio State University Comprehensive Cancer CenterColumbus, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05145400