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Study identifier: NCT05143996 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Condition: Relapsed/Refractory Acute Myeloid Leukemia (AML) · Myelodysplastic Syndrome (MDS)  ·  Sponsor: Cullinan Therapeutics Inc.

PhasePhase 1
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

CLN-049-001 is a Phase 1, open-label, multicenter, first-in-human trial of CLN-049 in patients with Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

This description comes directly from the study's public registry record.

Talk to the study team

Timna Serino  ·  +1 617 410 4650  ·  ClinOps@cullinantx.com

Always discuss trial participation with your own doctor first.

Locations (11)

University of Alabama O'Neal Cancer CenterBirmingham, Alabama, United StatesRecruiting
UCLALos Angeles, California, United StatesRecruiting
University of Miami Health SystemMiami, Florida, United StatesRecruiting
Moffitt Cancer CenterTampa, Florida, United StatesRecruiting
Emory University HospitalAtlanta, Georgia, United StatesRecruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesCompleted
Roswell Park Cancer InstituteBuffalo, New York, United StatesRecruiting
New York UniversityNew York, New York, United StatesRecruiting
Duke Cancer CenterDurham, North Carolina, United StatesRecruiting
Cincinnati Children's Hospital Medical CenterCincinnati, Ohio, United StatesWithdrawn
MD AndersonHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05143996