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Study identifier: NCT05142982 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Radiotherapy vs Observation for Post Chemotherapy Residual Mass in Advanced Seminoma

Condition: Seminoma  ·  Sponsor: Tata Memorial Centre

PhaseNA
Planned participants74
Who can joinMale, 18 Years to 80 Years
Healthy volunteersNo

About this study

Testicular tumors account for 1% of all cancers in males and germ cell tumors comprise 95% of all testicular cancers. Seminomas consist of around 50% of cases. However,adequate information is not there as 60- 80% residual disease is seen even after with the standard management of chemotherapy. With the advent of functional imaging there was hope that it could aid in more accurately targeting these tumors to systematically evaluate the role of PET-CT imaging in identifying patients diagnosed with stage IIB-IIIC seminomatous germ cell tumor, with residual visible tumor post chemotherapy who would benefit with loco regional radiotherapy. The therapeutic research in Seminomashas been relatively slow and such structured studies can allow analysis of large number of patients to report on acute and late effect of treatment outcomes using CTCAE and QOL (EORTC QLQ C-30) in these cancers. We hope that we will get help in identifying thrust areas for future research through this study.

This description comes directly from the study's public registry record.

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Contact details are listed per location below or on the registry record.

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Locations (2)

Tata Memorial CentreMumbai, Maharashtra, IndiaNot Yet Recruiting
Dr Vedang MurthyNavi Mumbai, Maharashtra, IndiaRecruiting

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Source record: clinicaltrials.gov/study/NCT05142982