Condition: Cancer · Cancer Diagnosis · Early Detection of Cancer · Sponsor: Avera McKennan Hospital & University Health Center
The purpose of this study is to characterize the breadth of molecular features present in participants receiving care within a large, integrated, community-based healthcare system. Through comprehensive genomic profiling, investigators aim to identify the underlying genomic drivers of premalignant and malignant conditions across a range of disease stages and cancer types. Comprehensive molecular profiling will include somatic tumor testing (tissue and/or blood) using next-generation sequencing. Selected subsets of samples may undergo whole exome and/or whole transcriptome sequencing for research purposes. Pharmacogenomic testing will also be performed to better understand individual variability in medication response and to identify opportunities for optimizing treatment. In addition, participants may optionally provide microbiome samples. To maximize the value of the genomic data, participants who consent to this protocol will have their electronic health records-both retrospective and prospective-abstracted, curated, annotated, and linked to the genomic data generated through study testing. Given the long-term value of these data, participants may also voluntarily consent to the storage of their biological samples in a biobank and to the use of their de-identified information for future research. Data collected from this participant population will support efforts to advance the understanding of cancer biology, as well as the discovery and validation of biomarkers associ…
This description comes directly from the study's public registry record.
Rachel Elsey, PharmD · 605-322-3225 · Rachel.Elsey@avera.org
Avera Precision Research Team · 888-422-1410 · McK-MBX-PrecisionResearch@avera.org
Always discuss trial participation with your own doctor first.
| Avera Cancer Institute - Marshall | Marshall, Minnesota, United States | Recruiting |
| Avera Cancer Institute - Aberdeen | Aberdeen, South Dakota, United States | Recruiting |
| Avera Cancer Institute - Mitchell | Mitchell, South Dakota, United States | Recruiting |
| Avera Cancer Institute - Pierre | Pierre, South Dakota, United States | Recruiting |
| Avera Cancer Institute | Sioux Falls, South Dakota, United States | Recruiting |
| Avera Cancer Institute - Yankton | Yankton, South Dakota, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05142033