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Study identifier: NCT05140525 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Effects of Combination Medical Therapy Followed by BPA on Right Ventricular-PA Coupling and Hemodynamics in CTEPH

Condition: CTEPH  ·  Sponsor: Dr Sudarshan Rajagopal

PhasePhase 3
Planned participants15
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The main goal of this study is to determine the effects of combination medical therapy (Riociguat and Macitentan) and balloon pulmonary angioplasty (BPA) on hemodynamics and right ventricular (RV) function (including advanced assessments of RV-pulmonary artery (PA) coupling from invasive hemodynamics) in participants with inoperable or post-PTE residual CTEPH.

This description comes directly from the study's public registry record.

Talk to the study team

Claudia Salazar  ·  +1 919 660 2026  ·  claudia.salazar@duke.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Duke University Medical CenterDurham, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05140525