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Study identifier: NCT05137665 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures

Condition: Amyotrophic Lateral Sclerosis · Movement Disorders · Degenerative Disorder  ·  Sponsor: Target ALS Foundation, Inc.

PhaseN/A
Planned participants1000
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

The goal of the study is to generate a biorepository of longitudinal biofluids-blood (plasma and serum), cerebral spinal fluid (CSF) and urine linked to genetics and longitudinal clinical information that are made available to the research community. To accomplish these goals, we will enroll 800 Amyotrophic Lateral Sclerosis (ALS) patients and 200 healthy controls from sites globally, over a 5 year time frame. Additionally, speech and motor function and spirometry measures will be collected bi-weekly in a subset of participants. ALS participants will be asked to come to the clinic for 5 study visits approximately every 4 months. Healthy participants will be coming for 2 study visits with a 12-month interval between visits. These samples and clinical information will be stored in a de-identified manner and made available for investigators to use in future research studies.

This description comes directly from the study's public registry record.

Talk to the study team

Laura Dugom, MPH  ·  919-440-2073  ·  laura.dugom@targetals.org

Robert Bowser, PhD  ·  602-406-8989  ·  robert.bowser@dignityhealth.org

Always discuss trial participation with your own doctor first.

Locations (12)

Barrow Neurological InstitutePhoenix, Arizona, United StatesRecruiting
University of California San DiegoSan Diego, California, United StatesRecruiting
Georgetown UniversityGeorgetown, District of Columbia, United StatesRecruiting
Mayo ClinicJacksonville, Florida, United StatesRecruiting
Northwestern UniversityChicago, Illinois, United StatesRecruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting
Washington UniversitySt Louis, Missouri, United StatesRecruiting
Columbia UniversityNew York, New York, United StatesRecruiting
Baylor College of MedicineHouston, Texas, United StatesRecruiting
University of WashingtonSeattle, Washington, United StatesRecruiting
Instituto RooseveltBogotá, ColombiaRecruiting
CHALS-CCT UPR MScienceSan Juan, Puerto RicoRecruiting

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Source record: clinicaltrials.gov/study/NCT05137665