Condition: Posttraumatic Stress Disorder · Sponsor: University of Haifa
Up-to-date, no studies have examined the attentional, sensory and emotional processing (difficulties) among patients diagnosed with Posttraumatic Stress Disorder (PTSD). In addition, the efficiency of drug treatments that focus on the noradrenergic and dopaminergic, and thus influence attention processing and PTSD symptoms through these pathways, have only briefly been investigated. There is well-established and long-standing evidence for the involvement of dopamine and noradrenaline in attentional function. This previously led to an investigation by the investigator's research lab in which the investigators hypothesized the involvement of an attentional disorder would influence PTSD symptoms in a rat model. Based on these results, the current study aims to characterize attentional deficits in patients with PTSD, as well as the correlation between attention, emotional regulation and sensory processing. The investigators do this partially by conducting a case-control study and through a subsequent double-blind RCT (with only the cases). The patients will be either treated with reboxetine + methylphenidate or placebo.
This description comes directly from the study's public registry record.
Avi Avital, PhD · +972-4-8420-364 · avitalavi@hotmail.com
Always discuss trial participation with your own doctor first.
| Emek Medical Center | Afula, Israel | Recruiting |
| University of Haifa | Haifa, Israel | Recruiting |
| Lev HaSharon Mental Health Center | Netanya, Israel | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05133804