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Study identifier: NCT05131022 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

Condition: Chronic Lymphocytic Leukemia (CLL) · Small Lymphocytic Lymphoma (SLL) · Diffuse Large B Cell Lymphoma (DLBCL)  ·  Sponsor: Nurix Therapeutics, Inc.

PhasePhase 1
Planned participants572
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a first-in-human Phase 1a/1b multicenter, open-label study designed to evaluate the safety and anti-cancer activity of NX-5948 in patients with advanced B-cell malignancies.

This description comes directly from the study's public registry record.

Talk to the study team

Additional Site Contact Information  ·  +1 (415) 417-3418  ·  clinicaltrials@nurixtx.com

Always discuss trial participation with your own doctor first.

Locations (62)

City of HopeDuarte, California, United StatesRecruiting
University of California, San FranciscoSan Francisco, California, United StatesRecruiting
Colorado Blood Cancer InstituteDenver, Colorado, United StatesRecruiting
Yale Cancer CenterNew Haven, Connecticut, United StatesRecruiting
University of MiamiMiami, Florida, United StatesRecruiting
Florida Cancer SpecialistsSarasota, Florida, United StatesRecruiting
Winship Cancer Institute of Emory UniversityAtlanta, Georgia, United StatesRecruiting
Northwestern UniversityChicago, Illinois, United StatesRecruiting
National Institute of HealthBethesda, Maryland, United StatesRecruiting
Cayuga Medical CenterIthaca, New York, United StatesWithdrawn
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesActive Not Recruiting
Duke University Medical CenterDurham, North Carolina, United StatesRecruiting

+ 50 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05131022