Condition: Ototoxic Hearing Loss · Sponsor: Sunnybrook Health Sciences Centre
One common side effect of cisplatin chemotherapy is ototoxicity. The drugs sodium thiosulfate and mannitol may protect against cisplatin-induced hearing loss. Specifically, sodium thiosulfate has been found to protect the cells in the inner ear, and may therefore prevent hearing loss. Mannitol can help sodium thiosulfate enter the inner ear, and ponteially increase the effectiveness of sodium thiosulfate. This study aims to assess the efficacy of sodium thiosulfate and mannitol to reduce the hearing impairment caused by cisplatin chemotherapy.
This description comes directly from the study's public registry record.
Yasmeen Aboulhawa · 1-416-480-6100 · yasmeen.aboulhawa@sri.utoronto.ca
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| Sunnybrook Health Sciences Centre | Toronto, Ontario, Canada | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05129748