Condition: Prostatic Neoplasm · Prostate Cancer · BRCA2 Mutation · Sponsor: Massachusetts General Hospital
This study aims to define the natural history of men at high genetic risk for prostate cancer on the basis of specific germline genetic mutations, family history, or Black/African ancestry and evaluate the utility of prostate MRI as a screening tool. The hypothesis is that this targeted population of men are at elevated risk of developing prostate cancer compared to the general population, and enhanced screening with MRI will enable early detection and diagnosis of potentially aggressive prostate cancer, characterization of the penetrance of specific mutations, and potentially identify new genetic risk mutations.
This description comes directly from the study's public registry record.
Olympia Price · 857-238-3838 · oprice@partners.org
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| Massachusetts General Hospital | Boston, Massachusetts, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05129605