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Study identifier: NCT05125055 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Neoadjuvant Anti-PD-1 and TP Versus TPF on Pathological Response in OSCC

Condition: Oral Squamous Cell Carcinoma · Neoadjvant Therapy · Anti-PD-1  ·  Sponsor: Shanghai Jiao Tong University School of Medicine

PhasePhase 2/Phase 3
Planned participants80
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

To compare the pathological efficacy of neoadjuvant Toripalimab and Albumin paclitaxel /Cisplatin (TTP) with Docetaxel/ Cisplatin/ 5-flurouracil (TPF) for patients with locally advanced resectable oral squamous cell carcinoma (OSCC), and to determine the safety of neoadjuvant TTP. In order to explore a better protocol of neoadjuvant therapy to improve the efficacy in patients with locally advanced OSCC.

This description comes directly from the study's public registry record.

Talk to the study team

Lai-ping Zhong, MD, PhD  ·  +862123271699  ·  zhonglp@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Ninth People's Hospital, Shanghai Jiao Tong University School of MedicineShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05125055