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Study identifier: NCT05121051 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Testing the Effect of the Broccoli Seed and Sprout Extract, Avmacol ES, on the Cancer Causing Substances of Tobacco in Heavy Smokers

Condition: Cigarette Smoking-Related Carcinoma  ·  Sponsor: National Cancer Institute (NCI)

PhasePhase 2
Planned participants135
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

This phase II trial tests whether broccoli seed and sprout extract works to break down cancer causing substances of tobacco in heavy smokers. Smokers are at increased risk for developing lung, head and neck, and other cancers. Broccoli seed and sprout extract may help break down and remove toxic substances caused by tobacco use and possibly produce substances that may protect cells from tobacco smoke-induced damage in current smokers.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

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Locations (3)

University of Arizona Cancer Center - Prevention Research ClinicTucson, Arizona, United StatesRecruiting
George Washington University Medical CenterWashington D.C., District of Columbia, United StatesRecruiting
Roswell Park Cancer InstituteBuffalo, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05121051