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Study identifier: NCT05119179 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Pharmacogenetics of the Response to GLP-1 in Mexican-Americans With Prediabetes

Condition: PreDiabetes  ·  Sponsor: The University of Texas Health Science Center, Houston

PhasePhase 4
Planned participants300
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This project uses both transcriptomic- and genomic-level data to identify mechanisms of individual responses to glucagon-like peptide-1 (GLP-1) in Mexican-Americans with prediabetes. The GLP-1 hormone is essential for glucose reduction, weight loss, cardiovascular risk reduction, and renal protection. Newly discovered mechanisms will illuminate causal links between disease genotype and phenotype, which may ultimately guide personalized therapeutic approaches for type 2 diabetes, prediabetes, obesity, cardiovascular disease, renal disease, and other related diseases.

This description comes directly from the study's public registry record.

Talk to the study team

Norma Perez-Olazaran  ·  (956) 755-0695  ·  Norma.P.PerezOlazaran@uth.tmc.edu

Rocio Uribe  ·  (956) 882-5165  ·  Rocio.D.Uribe@uth.tmc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UTHealth Clinical Research Unit (CRU) at UT BrownsvilleBrownsville, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05119179