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Study identifier: NCT05117398 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Dalbavancin Versus Standard Antibiotic Therapy for Catheter-related Bloodstream Infections Due to Staphylococcus Aureus

Condition: Catheter Bacteremia · Staphylococcus Aureus Infection  ·  Sponsor: Assistance Publique - Hôpitaux de Paris

PhasePhase 3
Planned participants406
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The primary objective of the study is to demonstrate, among patients with non-complicated CR-BSIs due to S. aureus, that a single-dose of intravenous (IV) dalbavancin 1500 mg is non-inferior to standard documented antibiotic therapy for 14 days according to national guidelines at DAY 30 (Long follow up visit). As the secondary objectives, the study aims to evaluate according to treatment group: 1. Cure rate at DAY 14 and DAY 90 (EOS); 2. Mortality rate within 90 days of follow-up; 3. Time to negativation of blood cultures; 4. Patient's quality of life; 5. Hospitalization length of stay; 6. Cost-utility analyses; 7. Occurrence of any adverse event (AE and SAE), until Day 90 (EOS).

This description comes directly from the study's public registry record.

Talk to the study team

Bernard CASTAN, MD  ·  +33 5 53 45 26 00  ·  bernard.castan@ch-perigueux.fr

Aurélien DINH, MD, PhD  ·  +33 1 47 10 44 32  ·  aurelien.dinh@aphp.fr

Always discuss trial participation with your own doctor first.

Locations (2)

Infectious Diseases Department, Raymond-Poincaré Hospital - APHPGarches, FranceNot Yet Recruiting
Infectious Diseases Department, CH PERIGUEUXPérigueux, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT05117398