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Study identifier: NCT05114876 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Redesigning the Surgical Pathway (PROMoTE)

Condition: Delirium · Cognitive Impairment · Perioperative/Postoperative Complications  ·  Sponsor: Sunnybrook Health Sciences Centre

PhaseNA
Planned participants260
Who can joinAll sexes, 60 Years to no upper limit
Healthy volunteersNo

About this study

Cognitive complications, that is problems with thinking and memory, are incredibly common after surgery, occurring in 10-50% of all older surgical patients. These complications can take different forms, but one of the most common is postoperative delirium (POD), a short-term state of confusion. In addition to being stressful for patients and their families, POD is linked to longer hospital stays, increased costs, higher mortality rates and other problems after surgery. Despite this, POD is often not recognized by doctors and there are currently no effective medications to treat POD. However, simple strategies such as helping patients to sleep properly and remain hydrated, have been shown to help. This study is testing if a delirium-reduction program will reduce postoperative delirium (POD) in older surgical patients. The investigators will first test memory and thought processes before surgery to find people who are most likely to develop POD. Once these people have been identified, they will be enrolled in a program which includes recommendations for their care team (e.g. surgeon, anesthesiologist, nurses) as well as educational materials for them and their family related to things that can be done to prevent delirium. By identifying at-risk patients and making sure that their doctors and caregivers are aware of how to prevent delirium, the investigators expect that this study will make surgery safer for older surgical patients.

This description comes directly from the study's public registry record.

Talk to the study team

Stephen Choi, MD, MSc  ·  416-480-4864  ·  stephen.choi@sunnybrook.ca

Lilia Kaustov, PhD  ·  416-480-6100  ·  lilia.kaustov@sunnybrook.ca

Always discuss trial participation with your own doctor first.

Locations (1)

Sunnybrook Health Sciences CentreToronto, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT05114876