Condition: Preterm Birth · Premature Birth · Complication of Prematurity · Sponsor: McMaster University
Antenatal corticosteroids (ACS) reduce the risks of neonatal death and morbidities in preterm infants, such as respiratory distress syndrome. The standard of care for pregnant people at risk of preterm birth includes 2 doses of Celestone (for a total of 24 mg in Canada, or 22.8 mg in Australia) to accelerate fetal lung maturity. The investigators plan to conduct a randomized controlled trial to determine whether half the usual dose (12 mg in Canada, or 11.4 mg in Australia) of Celestone is non-inferior to the standard double doses.
This description comes directly from the study's public registry record.
Sarah D McDonald, MD,MSc,FRCSC · 905-525-9140 · mcdonals@mcmaster.ca
SNACS Coordinating Centre · SNACS@sunnybrook.ca
Always discuss trial participation with your own doctor first.
| University of Calgary, Cumming School of Medicine | Calgary, Alberta, Canada | Recruiting |
| Alberta Health Services; University of Alberta | Edmonton, Alberta, Canada | Recruiting |
| Royal Columbian Hospital | New Westminster, British Columbia, Canada | Not Yet Recruiting |
| Fraser Health, University of British Columbia; Jim Pattison Outpatient Care and Surgery Centre | Surrey, British Columbia, Canada | Not Yet Recruiting |
| University of British Columbia; BC Women's Hospital | Vancouver, British Columbia, Canada | Not Yet Recruiting |
| Victoria General Hospital | Victoria, British Columbia, Canada | Not Yet Recruiting |
| University of Manitoba, Health Sciences Centre | Winnipeg, Manitoba, Canada | Not Yet Recruiting |
| University of Manitoba; St. Boniface General Hospital | Winnipeg, Manitoba, Canada | Not Yet Recruiting |
| Dr. Everett Chalmers Regional Hospital | Fredericton, New Brunswick, Canada | Recruiting |
| The Moncton Hospital, Horizon Health Network | Moncton, New Brunswick, Canada | Recruiting |
| Memorial University, Eastern Health | St. John's, Newfoundland and Labrador, Canada | Not Yet Recruiting |
| Dalhousie University; Izaak Walton Killam Health | Halifax, Nova Scotia, Canada | Recruiting |
+ 13 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT05114096