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Study identifier: NCT05113004 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

New Clinical End-points in Patients With Primary Sjögren's Syndrome

Condition: Primary Sjögren's Syndrome (pSS)  ·  Sponsor: Assistance Publique - Hôpitaux de Paris

PhasePhase 2
Planned participants300
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

There are no approved treatments for pSS and the clinical endpoints currently used in clinical trials are inadequate to capture all aspects of the disease that should be evaluated in clinical trials. The newly developed composite endpoint: Sjögren's Tool for Assessing Response to treatment (STAR) will allow a more specific and meaningful assessment of treatment efficacy in pSS. Because of the heterogeneity of the disease and of the central role of the interplay between B- and T-cells in the pathogenesis, it is worth to evaluate combination of conventional synthetic immunomodulatory drugs targeting both B- and T-cells.

This description comes directly from the study's public registry record.

Talk to the study team

Xavier MARIETTE  ·  01.45.21.37.51  ·  xavier.mariette@aphp.fr

Jacques-Eric GOTTENBERG  ·  03 88 12 79 53  ·  jacques-eric.gottenberg@chru-strasbourg.fr

Always discuss trial participation with your own doctor first.

Locations (7)

Valérie DevauchelleBrest, FranceRecruiting
Eric HachullaLille, FranceRecruiting
Jacques MorelMontpellier, FranceRecruiting
Véronique Le GuernParis, FranceRecruiting
Jacques-Eric GottenbergStrasbourg, FranceRecruiting
Christophe RichezTalence, FranceRecruiting
Raphaele SerorLe Kremlin-Bicêtre, Île-de-France Region, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT05113004