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Study identifier: NCT05112549 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Intrathecal Application of PD1 Antibody in Metastatic Solid Tumors With Leptomeningeal Disease (IT-PD1/ NOA 26)

Condition: Leptomeningeal Disease  ·  Sponsor: University Hospital Tuebingen

PhasePhase 1
Planned participants46
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

To determine the safety of intrathecal (IT) PD1 antibody for Intrathecal application of PD1 antibody in metastatic solid tumors with leptomeningeal disease of solid tumors.

This description comes directly from the study's public registry record.

Talk to the study team

Ghazaleh Tabatabai, Prof.Dr.  ·  +49 (0) 7071 - 2985018  ·  ghazaleh.tabatabai@uni-tuebingen.de

Always discuss trial participation with your own doctor first.

Locations (9)

Universitätsklinikum BonnBonn, GermanyRecruiting
University Hospital Freiburg, NeurosurgeryFreiburg im Breisgau, GermanyRecruiting
University Hospital Heidelberg, NeurooncologyHeidelberg, GermanyNot Yet Recruiting
SLK-Kliniken Heilbronn GmbH KlinikHeilbronn, GermanyRecruiting
University Hospital Mannheim, Neurology ClinicMannheim, GermanyRecruiting
Klinikum rechts der Isar/Technische Universität MünchenMünchen, GermanyRecruiting
Katharinenhospital StuttgartStuttgart, GermanyRecruiting
University Hospital Tübingen, NeurooncologyTübingen, GermanyRecruiting
University Hospital Ulm, ECTU - Early Clinical Trail UnitUlm, GermanyRecruiting

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Source record: clinicaltrials.gov/study/NCT05112549