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Study identifier: NCT05110937 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Dysfunctional Myelopoiesis and Myeloid-Derived Suppressor Cells in Sepsis

Condition: Sepsis · Trauma Injury  ·  Sponsor: University of Florida

PhaseN/A
Planned participants450
Who can joinAll sexes, 18 Years to 100 Years
Healthy volunteersYes

About this study

Adverse outcomes in surgical sepsis patients are secondary to dysregulated emergency myelopoiesis, and expansion of myeloid-derived suppressor cells. Here we propose to determine the underlying mechanisms behind the increased expansion of these leukocyte populations and the underlying mechanisms that drive inflammation and immune suppression.

This description comes directly from the study's public registry record.

Talk to the study team

Jennifer Lanz, MSN  ·  352-273-5497  ·  jennifer.lanz@surgery.ufl.edu

Ruth Davis, BSN  ·  352-273-5897  ·  ruth.davis@surgery.ufl.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UF Health at Shands hospitalGainesville, Florida, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05110937