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Study identifier: NCT05110066 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

BPA vs. PEA in CTEPH

Condition: Chronic Thromboembolic Pulmonary Hypertension  ·  Sponsor: University of Aarhus

PhaseNA
Planned participants139
Who can joinAll sexes, 18 Years to 79 Years
Healthy volunteersNo

About this study

Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare and potentially life-threatening progressive disease that evolves from unresolved pulmonary embolism. Gold standard treatment for CTEPH is pulmonary endarterectomy (PEA) performed by skilled cardio-thoracic surgeons. Some patients may not be surgical candidates due to co-morbidities or because the vascular lesions are too distal making them technically inoperable. In these patients, balloon pulmonary angioplasty (BPA) has emerged as an effective treatment. In a subgroup of patients, the distribution of vascular lesions makes it possible to perform either BPA or PEA. There has never been a head-to head comparison of BPA with PEA. The aim of this study is therefore, to evaluate if BPA is non-inferior to PEA in patients with (CTEPH) who are eligible for both treatments.

This description comes directly from the study's public registry record.

Talk to the study team

Asger Andersen, MD, ass.prof.  ·  40138052  ·  asger.andersen@clin.au.dk

Kristina Laut Matzen, RN,PhD  ·  +4521673903  ·  krlaut@clin.au.dk

Always discuss trial participation with your own doctor first.

Locations (2)

Aarhus University HospitalAarhus, DenmarkRecruiting
Royal PpworthCambridge, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT05110066