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Study identifier: NCT05103566 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Safety, Feasibility, and Efficacy of Non-invasive Vagus Nerve Stimulation (nVNS) in the Treatment of Aneurysmal Subarachnoid Hemorrhage

Condition: Subarachnoid Hemorrhage, Aneurysmal  ·  Sponsor: Massachusetts General Hospital

PhaseNA
Planned participants25
Who can joinAll sexes, 18 Years to 85 Years
Healthy volunteersNo

About this study

This is a single-site, single-arm, open-label pilot study assessing the safety, feasibility, and efficacy of non-invasive vagus nerve stimulation (nVNS), gammaCore, for the acute treatment of aneurysmal subarachnoid hemorrhage (SAH) subjects in a neurocritical care setting. 25 patients will be enrolled, all treated with an active device. The primary efficacy outcomes are reduced aneurysm rupture rate, reduced seizure and seizure-spectrum activity, minimized hemorrhage grades, and increased survival.

This description comes directly from the study's public registry record.

Talk to the study team

Aman B Patel, MD  ·  617-726-3303  ·  abpatel@mgh.harvard.edu

Austin R Birmingham, BS  ·  617-643-5547  ·  abirmingham@mgh.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05103566