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Study identifier: NCT05100966 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

FitJoints: Getting Fit for Hip and Knee Replacement

Condition: Hip Osteoarthritis · Knee Osteoarthritis  ·  Sponsor: McMaster University

PhaseNA
Planned participants192
Who can joinAll sexes, 60 Years to no upper limit
Healthy volunteersNo

About this study

Total hip or knee replacement is an important and cost-effective surgical intervention to relieve pain and improve independence and function in patients with osteoarthritis. The number of people waiting for elective surgeries has spiked in the COVID-19 pandemic. Prior to COVID-19, up to 40% of patients receiving joint replacement were frail and this number is rapidly increasing with longer wait-times and deconditioning associated with COVID-19 physical distancing. There is an urgent need to be responsive to the evolving challenges of healthcare. The proposed study is the first multi-site randomized controlled trial (RCT) to examine whether a multimodal frailty reduction intervention before surgery will improve postsurgical outcomes for this population. The COVID-19 adapted hybrid model includes a multimodal frailty intervention that may be implemented either in person or virtually and is aligned with international consensus guidelines on frailty reduction. To utilize the FitJoints multimodal frailty intervention to build resilience of patients undergoing joint replacement surgery to improve post-operative outcomes. The investigators hypothesize the FitJoints multimodal frailty intervention, with exercise, nutrition and medication optimization, will reduce frailty and pain while improving function and quality of life. Building upon the success of the FitJoints feasibility study (n=69) in Hamilton, Ontario, in the proposed multi-site RCT (n=192), older adults (≥60 years) unde…

This description comes directly from the study's public registry record.

Talk to the study team

Alexandra Papaioannou, MD, MSc  ·  (905) 521-2100  ·  papaioannou@hhsc.ca

George Ioannidis, MSc, PhD  ·  ioannidis@hhsc.ca

Always discuss trial participation with your own doctor first.

Locations (4)

Foothill Medical Centre - Alberta Health ServicesCalgary, Alberta, CanadaNot Yet Recruiting
Juravinski Hospital - Hamilton Health SciencesHamilton, Ontario, CanadaRecruiting
St. Joseph's HealthcareHamilton, Ontario, CanadaNot Yet Recruiting
University Hospital - London Health Sciences CentreLondon, Ontario, CanadaNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT05100966