Condition: Sickle Cell Disease · Attention Deficit · Cognitive Deficit in Attention · Sponsor: Children's National Research Institute
Children with sickle cell disease (SCD) exhibit significantly reduced cognitive functioning (often difficulties with attention) compared to peers and siblings without SCD. EndeavorRx (Akili Interactive Labs: Boston, MA) is an FDA-approved home-based, electronic attentional-control training program designed to treat attention problems in youth. Users access EndeavorRx on a tablet device for 25-30 minutes each day, 5 days per week, for 4 weeks. The program involves training in a game-like environment that repeatedly challenges attentional-control abilities and adapts to user performance, becoming more difficult over time as performance improves. This pilot study is examining the feasibility, acceptability, and preliminary efficacy of EndeavorRx in a sample of 20 children with SCD ages 8-16 who are being treated with chronic blood transfusion therapy.
This description comes directly from the study's public registry record.
Steven J Hardy, Ph.D. · 202-476-5000 · sjhardy@childrensnational.org
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| Children's National Hospital | Washington D.C., District of Columbia, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05099874