Condition: Anatomic Stage IV Breast Cancer AJCC v8 · Clinical Stage IV Cutaneous Melanoma AJCC v8 · Locally Advanced Cutaneous Melanoma · Sponsor: Fred Hutchinson Cancer Center
This phase I trial studies the safety of personalized neo-antigen peptide vaccine in treating patients with stage IIIC-IV melanoma, hormone receptor positive HER2 negative breast cancer that has spread from where it first started (primary site) to other places in the body (metastatic) or does not respond to treatment (refractory) or stage III-IV non-small cell lung cancer. Personalized neo-antigen peptide vaccine is a product that combines multiple patient specific neo-antigens. Given personalized neo-antigen peptide vaccine together with Th1 polarizing adjuvant poly ICLC may induce a polyclonal, poly-epitope, cytolytic T cell immunity against the patient's tumor.
This description comes directly from the study's public registry record.
FHCC Intake · 206-606-1024 · hutchdoc@fredhutch.org
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| Fred Hutch/University of Washington Cancer Consortium | Seattle, Washington, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05098210