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Study identifier: NCT05098119 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Neoadjuvant Sintilimab Combined With Reduction of Cycles of Chemotherapy in Resectable Oral Cavity or Oropharyngeal Squamous Cell Carcinoma (OOC-002)

Condition: Oral Cavity Squamous Cell Carcinoma · Oral Squamous Cell Carcinoma · Oropharyngeal Squamous Cell Carcinoma  ·  Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

PhasePhase 2
Planned participants43
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

The study is being conducted to evaluate the efficacy and safety of sintilimab in combination with reduction of cycles of chemotherapy (carboplatin and nab-paclitaxel) in patients with oral cavity or oropharyngeal squamous cell carcinoma who are about to undergo surgery. Data obtained in this trial will provide valuable information for planning further prospective clinical trials of anti-PD-1 and other immunotherapies in oral cavity or oropharyngeal squamous cell carcinoma.

This description comes directly from the study's public registry record.

Talk to the study team

Song Fan, Doctor degrees  ·  020-81332220  ·  fansong2@mail.asysu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Sun Yat-sen Memorial HospitalGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05098119