Condition: Total Knee Arthroplasty · Sponsor: Rush University Medical Center
The purpose of this study is to evaluate the efficacy of an oral methylprednisolone taper on acute postoperative pain, function, opioid consumption, nausea, and complications following outpatient total knee arthroplasty (TKA). We hypothesize that administration of an oral methylprednisolone taper starting on postoperative day 1 (POD 1) following TKA will be associated with improved pain and decreased opioid use, nausea, and complications at POD1-7, as compared to similar patients who receive placebo. Additionally, those taking methylprednisolone will report decreased pain and greater objective functional outcomes at 3 and 6 weeks postoperatively as compared to controls.
This description comes directly from the study's public registry record.
Anne DeBenedetti · 3124322468 · anne.debenedetti@rushortho.com
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| Rush Oak Brook Outpatient Center | Oak Brook, Illinois, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05097976