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Study identifier: NCT05095857 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

The Anaesthetic Ketamine as Treatment for Patients With Severe Acute Brain Injury

Condition: Subarachnoid Hemorrhage, Aneurysmal · Intracerebral Hemorrhage · Traumatic Brain Injury  ·  Sponsor: Rigshospitalet, Denmark

PhasePhase 4
Planned participants400
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Cortical spreading depolarisations are pathological depolarisation waves that occur frequently after severe acute brain injury and has been associated with poor outcome. S-ketamine has been shown to inhibit cortical spreading depolarisations. The aim of the present study is to examine the efficacy and safety of using S-ketamine for treatment of patients with severe acute brain injury, as well as the feasibility of the trial design.

This description comes directly from the study's public registry record.

Talk to the study team

Trine H Andreasen, MD  ·  +4535455982  ·  trine.hjorslev.andreasen@regionh.dk

Kirsten Møller, Professor  ·  Kirsten.Moeller.01@regionh.dk

Always discuss trial participation with your own doctor first.

Locations (1)

RigshospitaletCopenhagen, DenmarkRecruiting

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Source record: clinicaltrials.gov/study/NCT05095857