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Study identifier: NCT05092984 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Evaluation of Spironolactone Efficacy in Patient with Rheumatoid Arthritis (RA)

Condition: Rheumatoid Arthritis  ·  Sponsor: University Hospital, Strasbourg, France

PhasePhase 3
Planned participants154
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Evaluation of spironolactone, a well-known cardiological treatment, in patients with rheumatoid arthritis (RA). The hypothesis is that spironolactone, through its anti-inflammatory and anti-fibrosis actions, decreases RA's activity. The primary objective is to assess the efficacy of spironolactone on RA activity by evaluating the proportion of patients achieving DAS28-CRP \< 3.2 at 3 months (comparison between spironolactone and placebo arms). CRP (C reactive protein)

This description comes directly from the study's public registry record.

Talk to the study team

Jacques-Eric GOTTENBERG, Professor  ·  3 88 12 79 53  ·  jacques-eric.gottenberg@chru-strasbourg.fr

Always discuss trial participation with your own doctor first.

Locations (1)

University Hospital, Strasbourg, FranceStrasbourg, Alsace, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT05092984