Condition: Ovarian Cancer · Relapsed Ovarian Cancer · Fallopian Tube Cancer · Sponsor: University College, London
ACTOv will compare standard 3-weekly carboplatin (AUC5), to carboplatin delivered according to an AT regimen. The AT regimen will modify carboplatin dose according to changes in the clinical-standard serum biomarker CA125 as a proxy measure of total tumour burden and an individual patient's response to the most recent chemotherapy treatment. AT could prolong sensitivity to carboplatin and extend tumour control, while simultaneously reducing chemotherapy dose and drug-induced toxicity. Carboplatin is a low cost and low toxicity drug that has an enduring and central role in ovarian cancer treatment.
This description comes directly from the study's public registry record.
ACTOv Trial Coordinator · 02076794466 · ctc.actov@ucl.ac.uk
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| University College London Hospitals | London, United Kingdom | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05080556