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Study identifier: NCT05077735 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Stereotactic Biopsy Split-Course Radiation Therapy in Diffuse Midline Glioma, SPORT-DMG Trial

Condition: Diffuse Midline Glioma, H3 K27M-Mutant  ·  Sponsor: Mayo Clinic

PhasePhase 2
Planned participants32
Who can joinAll sexes, 1 Year to no upper limit
Healthy volunteersNo

About this study

This phase II trial studies the clinical outcomes of hypofractionated radiation therapy in patients with diffuse midline gliomas. This study aims to change the way radiation is delivered, from giving 6 weeks of radiation all at once to giving 2 weeks of radiation. This may determine if there is a difference in the outcome of the treatment, and most importantly, the patients' quality of life.

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Trials Referral Office  ·  855-776-0015  ·  mayocliniccancerstudies@mayo.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Mayo Clinic Hospital in ArizonaPhoenix, Arizona, United StatesRecruiting
Mayo Clinic in RochesterRochester, Minnesota, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05077735