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Study identifier: NCT05061550 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer

Condition: Non-small Cell Lung Cancer  ·  Sponsor: AstraZeneca

PhasePhase 2
Planned participants630
Who can joinAll sexes, 18 Years to 95 Years
Healthy volunteersNo

About this study

The study is intended to assess the safety and efficacy of perioperative treatment with Durvalumab in combination with Oleclumab, Monalizumab, or AZD0171 and platinum doublet chemotherapy (CTX); or Volrustomig or Rilvegostomig in combination with CTX; or Datopotamab deruxtecan (Dato-DXd) in combination with Durvalumab or Rilvegostomig and single agent platinum chemotherapy in participants with resectable, early-stage non-small cell lung cancer.

This description comes directly from the study's public registry record.

Talk to the study team

AstraZeneca Clinical Study Information Center  ·  1-877-240-9479  ·  information.center@astrazeneca.com

AstraZeneca Lung Cancer Study Locator Service  ·  1-884-432-3892  ·  az-lcsl@careboxhealth.com

Always discuss trial participation with your own doctor first.

Locations (97)

Research SiteLittle Rock, Arkansas, United StatesRecruiting
Research SiteLos Angeles, California, United StatesRecruiting
Research SiteOakland, California, United StatesWithdrawn
Research SiteNew Haven, Connecticut, United StatesRecruiting
Research SiteStuart, Florida, United StatesCompleted
Research SiteGainesville, Georgia, United StatesCompleted
Research SiteChicago, Illinois, United StatesRecruiting
Research SiteBaltimore, Maryland, United StatesWithdrawn
Research SiteBaltimore, Maryland, United StatesRecruiting
Research SiteBoston, Massachusetts, United StatesRecruiting
Research SiteSaint Louis Park, Minnesota, United StatesCompleted
Research SiteOmaha, Nebraska, United StatesRecruiting

+ 85 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05061550