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Study identifier: NCT05057806 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

SGLT2 Inhibitors, Ketones, and Cardiovascular Benefit Research Plan

Condition: Type2 Diabetes · Heart Failure With Preserved Ejection Fraction  ·  Sponsor: The University of Texas Health Science Center at San Antonio

PhaseEARLY_Phase 1
Planned participants30
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

The study team will examine the effects of SGLT2i (and SGLT2i-induced increases in plasma ketone concentrations) on skeletal muscle and cardiac ketone uptake, skeletal muscle bioenergetics, cardiopulmonary exercise capacity, and patient-reported functional outcomes.

This description comes directly from the study's public registry record.

Talk to the study team

Carolina Solis-Herrera, MD  ·  210-567-4900  ·  solisherrera@uthscsa.edu

Francisca M Acosta, PhD  ·  210-450-8677  ·  acostafm@uthscsa.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Texas Health Science Center at San AntonioSan Antonio, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05057806