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Study identifier: NCT05053802 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Efficiency and Safety of Microwave Ablation Plus Immune Checkpoint Inhibitor for Patients With Multiple Primary Lung Cancer: A Open, Multi-center, Phase II Clinical Trial

Condition: Multiple Primary Lung Cancer  ·  Sponsor: Shanghai Pulmonary Hospital, Shanghai, China

PhasePhase 2
Planned participants146
Who can joinAll sexes, 18 Years to 79 Years
Healthy volunteersNo

About this study

Prospective, multi-center, phase II clinical trial. The study plans to enroll 146 patients with multiple lung cancers. After signing the informed consent, they were screened to meet the admission and discharge criteria, and received microwave ablation treatment. Electromagnetic navigation bronchoscope-guided intrapulmonary microwave ablation or percutaneous microwave ablation was selected according to the patient's wishes and the evaluation of the surgeon. After the operation, they were randomized and the experimental group accepted PD-1 immune checkpoint inhibitor treatment (microwave ablation combined with Camrelizumab treatment does not exceed 16 cycles, or disease progression/worsening or confirmed imaging disease progression, or withdrawal for any reason), the control group does not After receiving any treatment, the two groups were followed up closely (36 months after the last treatment, including safety follow-up and survival follow-up).

This description comes directly from the study's public registry record.

Talk to the study team

Chang Chen, Dr  ·  65115006  ·  2031222@tongji.edu.cn

Always discuss trial participation with your own doctor first.

Locations (6)

Changhai HospitalShanghai, Shanghai Municipality, ChinaRecruiting
Shanghai First People's HospitalShanghai, Shanghai Municipality, ChinaRecruiting
Shanghai Pulmonary HospitalShanghai, Shanghai Municipality, ChinaRecruiting
Ruijin HospitalShanghai, Shanghai Municipality, ChinaRecruiting
Shanghai Tenth People's HospitalShanghai, Shanghai Municipality, ChinaRecruiting
Renji HospitalShanghai, Shangh, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05053802