Condition: Endometrial Cancer · Cervical Cancer · Atypical Endometrial Hyperplasia · Sponsor: Mayo Clinic
The overarching objective of this project is to develop a pan-gynecologic cancer detection test using gynecologic (unique endometrial, cervical, and ovarian cancer) cancer-specific methylated DNA markers and high-risk human papilloma virus (HR-HPV) detected in vaginal fluid and/or plasma. This proposal defines Phase II MDM-based cancer detection studies in endometrial cancer (EC) and endometrial hyperplasia with atypia (AEH) in vaginal fluid and 2) ovarian cancer (OC) in plasma and vaginal fluid. Additionally, it defines necessary Phase I MDM-based cancer detection and exploratory aims to test novel cervical cancer (CC) MDMs and test the specificity of cancer-specific MDMs among various common benign gynecologic pathologies.er detection and exploratory aims to test novel cervical cancer MDMs and test the specificity of cancer-specific MDMs among various common benign gynecologic pathologies.
This description comes directly from the study's public registry record.
Maureen A Lemens, BSN · 507-293-1487 · lemens.maureen@mayo.edu
Clinical Trials Referral Office · 855-776-0015 · mayocliniccancerstudies@mayo.edu
Always discuss trial participation with your own doctor first.
| Mayo Clinic | Phoenix, Arizona, United States | Recruiting |
| Mayo Clinic | Jacksonville, Florida, United States | Recruiting |
| My GYN Care | Miami, Florida, United States | Active Not Recruiting |
| Genoma Research, Inc. | Miami, Florida, United States | Recruiting |
| Orlando Health | Orlando, Florida, United States | Recruiting |
| Signature Women's Healthcare, LLC | Pembroke Pines, Florida, United States | Active Not Recruiting |
| Sarasota Memorial Health Care System | Sarasota, Florida, United States | Recruiting |
| Piedmont Healthcare | Atlanta, Georgia, United States | Recruiting |
| University of Chicago | Chicago, Illinois, United States | Recruiting |
| Providea Health Partners, LLC | Evergreen Park, Illinois, United States | Active Not Recruiting |
| Ochsner Clinic Foundation | New Orleans, Louisiana, United States | Recruiting |
| Valley OB-GYN Clinic | Saginaw, Michigan, United States | Recruiting |
+ 12 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT05051722