Condition: Pre-diabetes · Obesity · Sponsor: Philip Kern
The investigator hypothesizes that treatment with the ß3 agonist mirabegron results in improved glucose metabolism, including a reversal of prediabetes in obese, insulin-resistant human research participants, and this is further improved by combination therapy with tadalafil. The investigator will comprehensively analyze glucose homeostasis in prediabetic patients treated for 14 weeks with mirabegron, tadalafil or both drugs as compared to a placebo.
This description comes directly from the study's public registry record.
Zach Leicht · 859-218-1397 · zachary.leicht@uky.edu
Philip Kern, M.D. · 859-218-1394 · pake222@uky.edu
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| University of Kentucky | Lexington, Kentucky, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05051436